Progenika Inc


Gene Regulation Analysis

Knowledge of gene expression regulation and genetic interactions within each cell type are essential to evaluate molecular causes in multiple pathologies.

By using Affymetrix (Tilling Arrays) GeneChip® technology, a gene expression analysis complementary service is provided ranging from chIP-on-chip studies up to transcript mapping. This technology offers a wide scope of opportunities for researchers:

  • DNA methylation studies.
  • Mapping of transcription factors binding sites.
  • Research on new transcriptional elements

1. RNA EXTRACTION AND PURIFICATION SERVICE

Progenika Biopharma puts at your disposal an optional RNA extraction and purification service to facilitate processing of the starting material.

2. PROCESSING

QUALITY CONTROL, LABELING, HIBRIDIZATION, SCANNING, PRESENTATION OF NUMERICAL DATA

Microarray processing includes the performance of the strictest quality controls to guarantee optimal and reliable results. Further to microarray scanning, numerical data presentation is performed.

3. BIOINFORMATICS UNIT

Statistical analysis of selected data is realized considering expression differences in each experimental condition. Next, statistical clustering grouping differentially-expressed genes according to associated function and biological processes allows biological interpretation of results.

All the information obtained so far is delivered to the client together with an extensive database including web links, GenBank notes, LocusLink and ontological information considering different biological processes, molecular function, subcellular location, metabolic pathways and signaling pathways.

Results are delivered to the client within a period of 21 days once the RNA sample quality is approved.

 

 

With the collaboration of: